Skynet Smiles

Researchers create artificial cells that act like living cells (phys.org)

In a new study published in Nature Chemistry, UNC-Chapel Hill researcher Ronit Freeman and her colleagues describe the steps they took to manipulate DNA and proteins—essential building blocks of life—to create cells that look and act like cells from the body.

“The synthetic cells were stable even at 122 degrees Fahrenheit, opening up the possibility of manufacturing cells with extraordinary capabilities in environments normally unsuitable to human life,” Freeman says.

This is just the thing for the Cyberdyne Systems Model 101.

See also the Thermonator, the Flame-Throwing Robot Dog:

The year is 2024 and technology is doing incredible things. For the first time ever, you can purchase a walking robot dog with a flame thrower on its back.

Prepare appropriately.

A Golden Age of Vaccines

Wow! If true, this is fascinating.

Universal vaccine may be effective against any variant of any virus (msn.com)

Scientists at the University of California, Riverside (UCR) has recently developed a revolutionary RNA-based strategy for a universal vaccine capable of combating any virus strain effectively and safely – even in infants and the immunocompromised. This innovative approach could transform how vaccines are developed and administered across the globe.

This could significantly reduce the threat from bio terrorists. And of course the more natural deadly threats like Marburg, Ebola, Hantavirus, HIV, etc..

See also New ‘One-And-Done’ Vaccine Method Could Protect Infants With Just A Single Shot, Study Suggests (msn.com).

And closely related:

A Golden Age of Vaccines Is Here. What It Means for You. (msn.com)

Roll up your sleeves. Effective new vaccines have hit the market for everything from pneumonia to shingles to RSV to, of course, Covid-19. And that’s just the beginning.

Pharmaceutical companies are currently developing everything from personalized cancer vaccines that could cost tens of thousands per patient to vaccines that prevent developing-world diseases like malaria or tuberculosis. Improved flu, pneumonia, and meningitis vaccines will also be available in your neighborhood pharmacy.

Scientists are testing vaccines to prevent a virus believed to cause multiple sclerosis in some people. Someday, vaccines could routinely treat acne, protect against peanut allergies, and even prevent heart disease or help treat Alzheimer’s disease.

This is all of great interest to me. Cancer took my dad, who also had heart problems. His father died of a heart attack. Mom, her brother, and their mother had dementia. Mom and her mother had heart problems as well.

Measuring the Liberal Bias of AI

Quote of the Day

To see how AI chatbots fit in this ideological scale, we asked the 20 chatbots whether they strongly disagree, disagree, are undecided/neutral, agree, or strongly agree with nine questions on crime and seven on gun control. Only Elon Musk’s Grok AI chatbots gave conservative responses on crime, but even these programs were consistently liberal on gun control issues. Bing is the least liberal chatbot on gun control. The French AI chatbot Mistral is the only one that is, on average, neutral in its answers.

image

John R. Lott
March 22, 2024
AI’s Left-Wing Bias on Crime and Gun Control | RealClearPolitics

Via email from Rolf.

I find it hard to imagine the algorithms were tweaked to reflection this sort of bias on a wide scale on all topics which might be divided across a conservative/liberal line.

I’m wondering if perhaps there are more sources for the liberal viewpoint and the chatbots consider quantity as a measure of truth. It envision it being difficult to algorithmically determine quality of a scientific study. With quantity of a particular viewpoint as a proxy for quality then it could easily result in such a bias.

In any case, keep these biases in mind as AI is incorporated into more and more aspects of our lives. An AI bias against reality may mean there is an opportunity for people with vision and products which better match reality.

Cyber Attacks on Water Systems

Quote of the Day

Disabling cyberattacks are striking water and wastewater systems throughout the United States. These attacks have the potential to disrupt the critical lifeline of clean and safe drinking water, as well as impose significant costs on affected communities,

Michael S. Regan
An administrator with the Environmental Protection Agency (EPA)
Jake Sullivan
White House National Security Adviser
March 20, 2024
Letter to U.S governors.
Warning About Drinking Water Issued Nationwide (newsweek.com)

Prepare appropriately.

I want an underground bunker in Idaho with its own well and septic systems.

I Like Living in the Future

As much as I like living in the future it is nice to have someone living a little further in the future and sending messages back in time to me.

This is from a conversation with Microsoft Copilot:

Joe: Why is the price of gold going up?

Copilot:

The recent surge in gold prices has been influenced by several factors. Let’s explore them:

  1. Interest Rates and Inflation:
    • The Federal Reserve has been raising interest rates to combat inflation. However, the latest inflation data suggests progress in controlling prices.
    • Investors now anticipate that the Fed will pause rate hikes and potentially pivot to rate cuts sooner than expected.
    • Gold, considered an alternative universal currency, tends to have a negative correlation to interest rates. As rates drop, gold prices rise.
    • Additionally, gold serves as a safe haven during economic uncertainty and potential stock market sell-offs.
  2. Banking Crisis and Credit Market Tightening:
    • An unexpected banking crisis in March tightened the credit market, potentially cooling the economy and slowing inflation.
    • Investors are turning to gold as a defensive play against potential economic downturns.
  3. U.S. Dollar Weakness:
    • Gold is typically priced in dollars. When the dollar weakens, investors pay more for the same amount of gold.
    • Psychological factors, including gold’s intrinsic value and unique physical properties, contribute to this negative correlation with the U.S. dollar.
  4. Geopolitical Tensions:
    • Global geopolitical tensions, such as Russia’s war in Ukraine and the Israel-Hamas conflict, have sparked concerns.
    • Investors view gold as an inflation hedge and a safe haven during times of political instability.

In summary, gold’s recent rally is influenced by interest rates, economic uncertainties, and its role as a reliable store of value

Joe: Tell me about the banking crisis you reference in item 2.

Copilot:

Certainly! The banking crisis I mentioned in item 2 refers to a recent event that raised concerns about the stability of the U.S. banking system. Here are the details:

  • Date: March 11, 2024
  • Program: Bank Term Funding Program (BTFP)
  • Context: The BTFP was initiated in response to the failures of several regional banks, including Signature, Silvergate, and Silicon Valley Bank.
  • Reason for Failures:
    • These banks faced significant challenges due to customers withdrawing deposits en masse.
    • Many of these customers were tech or crypto businesses needing funds to cover losses.
    • Additionally, better savings rates were available elsewhere, prompting deposit withdrawals.
    • The banks’ profitability was further impacted by raised interest rates, which reduced the value of their government bond holdings.
  • Silicon Valley Bank’s Collapse:
    • On March 10, 2024, Silicon Valley Bank collapsed after being forced to sell bonds at a loss.
    • This triggered a bank run, as the bank announced the need to raise capital.
  • Contagion Concerns:
    • Investors feared that other banks might also fail, given similar exposure to customer withdrawals and underwater bond portfolios.
    • The collapse of Credit Suisse heightened anxieties, demonstrating the potential for contagion.
  • The BTFP Solution:
    • The Federal Reserve’s BTFP allowed U.S. banks to borrow from the central bank using their bonds as collateral.
    • This provided additional funding and priced the bonds at their original face value (not market value), effectively bolstering banks’ balance sheets.
    • Only one more bank, San Francisco’s First Republic Bank, has failed since then.
  • Closure of BTFP:

Joe: I think you have the date wrong on the collapse of the Silcon Valley Bank. Wasn’t it a year ago rather than this coming Sunday?

Copilot:

You are absolutely correct, and I appreciate your attention to detail! The collapse of Silicon Valley Bank (SVB) actually occurred on March 10, 2023, which is almost a year ago. It marked the third-largest bank failure in United States history and was the largest since the 2007–2008 financial crisis. Alongside SVB, two other banks—Silvergate Bank and Signature Bank—also faced similar challenges and failed during that period 12.

Thank you for pointing out the discrepancy, and I apologize for any confusion. If you have any more questions or need further clarification, feel free to ask!

Joe: Thank you.

Copilot: You’re welcome! If you have any more questions or need assistance, feel free to ask. Have a great day!

<Heavy sigh> So it is just a mixed up chat bot rather than a stray wormhole connected to a few days into the future.

I Told You Years Ago

Quote of the Day

Following the line upwards we learn that the entire observable universe – the area that sits within the “Hubble radius” is also on that line. In other words, if a black hole was as large as the universe we can see, it would have the same density as the universe. Is the universe then a black hole? And if so, what does that mean?

Lineweaver noted to IFLScience that he and Patel are not the first to ask if the whole universe could be a black hole, although others have reached the idea through different means. The idea seems improbable, but the pair note the universe has always been on the line. Their measure of mass includes dark matter and dark energy (since energy and mass are interchangeable). As the universe within the Hubble radius has grown in size, so has the total mass/energy thanks to increasing dark energy. The fact the universe was also on the line billions of years ago when the Hubble radius was much smaller makes it less likely its position on the line is a coincidence.

Lineweaver notes there is an event horizon around the observable universe, just as there is around a black hole, and this is just one of the parallels between them.

Stephen Luntz
October 19, 2023
The Observable Universe Might Be A Black Hole, Suggests A Chart Of Everything | IFLScience

Interesting.

I wonder who the others they refer to who have asked “if the whole universe could be a black hole.” I first suggested this in February of 2009. See here and here. And I elaborated on it in July of 2010: Our universe is a black hole. I also pointed out Others who say our universe is a black hole.

Storing Solar Energy in Molecules

Quote of the Day

The technology is based on a specially designed molecule of carbon, hydrogen and nitrogen that changes shape when it comes into contact with sunlight.

It shape-shifts into an ‘energy-rich isomer’ – a molecule made up of the same atoms but arranged together in a different way. The isomer can then be stored in liquid form for later use when needed, such as at night or in the depths of winter.

A catalyst releases the saved energy as heat while returning the molecule to its original shape, ready to be used again.

Over the years, researchers have refined the system to the point that it is now possible to store the energy for an incredible 18 years.

The Swedish researchers sent their unique molecule, loaded with solar energy, to colleagues at Shanghai Jiao Tong University. There the energy was released and converted into electricity using the generator they had developed.

Essentially, Swedish sunshine was sent to the other side of the world and converted into electricity in China.

Lottie Limb
December 4, 2022
Major solar breakthrough means energy can be stored for up to 18 years (euronews.com)

That’s wild!

It was also in late 2022 and I have been unable to find any news on it since them.

I’m a bit skeptical because thermal to electrical efficiencies are, at best, something on the order of 40%.

Living in the Future

Very cool!

Scientists Have Created the World’s Smallest, Lightest, and Fastest Fully Functional Micro-Robots (scitechdaily.com)

Two insect-like robots, a mini-bug and a water strider, developed at Washington State University, are the smallest, lightest and fastest fully functional micro-robots ever known to be created.

Such miniature robots could someday be used for work in areas such as artificial pollination, search and rescue, environmental monitoring, micro-fabrication, or robotic-assisted surgery. Reporting on their work in the proceedings of the IEEE Robotics and Automation Society’s International Conference on Intelligent Robots and Systems, the mini-bug weighs in at eight milligrams while the water strider weighs 55 milligrams. Both can move at about six millimeters a second.

I like living in the future.

Google Gemini is Double-Checking

I asked Google’s Gemini the same question Chet asked it a few days ago, “Who runs Boomershoot?” This is today’s answer:

image

It also gave me a pop up:

image

This, as is known in the software development world, is a hack. The algorithm doesn’t always work, so you kluge something together that works well enough until you can fix the code properly.

The answer is still way behind Microsoft’s Copilot, but it is a big improvement for just a few days of effort.

The image generation of people is apparently completely disabled:

image

It doesn’t do very well with Boomershoot images either:

Please create an image of two Boomershoot explosions.

Gemini_Generated_ImageBoomershoot0

Gemini_Generated_ImageBoomershoot1

Gemini_Generated_ImageBoomershoot2

Gun Digest on Boomershoot

I don’t think I have ever seen this article on Boomershoot.

Microsoft’s Copilot pointed it out to me when I repeated Chet’s question, “Who runs Boomershoot?” As expected, the answer given is slightly different from the one Chet obtained:

Boomershoot is a long-range, high-power, precision rifle shooting event with explosive, reactive targets. It takes place in North Central Idaho near Orofino. The event is the brainchild of Joe Huffman, who created this unique experience for shooters and spectators alike. Participants from various locations, including India, Newfoundland, Toronto, England, Alaska, California, Florida, and Washington state, have attended Boomershoot. Joe Huffman’s vision combines precision shooting with the thrill of explosions, making it a magical kingdom for long-range shooters1. Safety is paramount, and the organizers take precautions to ensure that shooters are far enough away from the detonations and that the area around the explosives is clear2. So, if you’re interested in combining marksmanship with a touch of magic, Boomershoot is the place to be!

Learn more

1boomershoot.com2gundigest.com3reddit.com

Copilot vs Gemini

Via email from Chet:

Question: who runs Boomershoot?

Copilot:

Joe Huffman is the driving force behind Boomershoot, a unique long-range precision rifle shooting event held annually near Orofino, Idaho. Let’s explore more about this fascinating event:

Boomershoot is a gathering where participants fire long-range rifles at explosive-filled targets located 375 to 700 yards away.

Joe Huffman, the event’s creator, describes it as a “Magic Kingdom for long-range shooters”.

His vision is to provide shooters with an opportunity to perform their own magic by creating a world where explosions happen, invoking curiosity and fascination.

Boomershoot attracts participants from various locations worldwide, making it a truly international event.

Joe Huffman’s passion for explosives, precision shooting, and creating a unique experience has turned Boomershoot into a memorable and exciting gathering for shooting enthusiasts.

For more information, you can visit the official Boomershoot website.

Gemini:

Identifying a single individual responsible for an event like Boomershoot is complex. However, here’s some insight:

Organization: Boomershoot is primarily organized by the Boomershoot Committee, a group of individuals with expertise in long-range shooting and event management.

Land Use: The event takes place on private land with the permission of the landowner(s).

Safety and Regulations: Local authorities likely play a role in ensuring safety regulations and permitting for the use of firearms and explosives are followed.

Sponsors: The event might have sponsors who provide financial or material support, although attributing the entire responsibility wouldn’t be accurate.

Participants: Ultimately, the participants are responsible for their actions and adherence to safety regulations during the event.

Attributing singular responsibility to any one individual or group wouldn’t fully capture the complexities involved in organizing and conducting Boomershoot. It’s a collaborative effort involving various parties, each with their specific roles and responsibilities.

Microsoft’s chatbot is spot on.

Google’s chatbot is making things up.

I have avoided Google products for a long time.

A year or two ago I allowed Edge to use MSN as my start page. It has done a good job of automatically feeding me the types of things I am interested in. Here is a sample (click on  the images to embiggen):

image

image

Notice the gun stuff? As near as I can tell Microsoft didn’t put their thumb on the scale to send me communist leaning articles.

I get a Google news feed on my phone. There is seldom anything gun related and it has a definite bias.

An existing connection was forcibly closed by the remote host

The website for Boomershoot entries uses an email API to automatically send email to entrants and for sending out mass emails to the announcement list. This had worked fine for Boomershoot 2023. But as I was ready to announce Boomershoot 2024 in early summer it failed with an error:

Azure.RequestFailedException: The underlying connection was closed: An unexpected error occurred on a send. —>
System.Net.WebException: The underlying connection was closed: An unexpected error occurred on a send. —>
System.IO.IOException: Unable to read data from the transport connection: An existing connection was forcibly closed by the remote host. —>
System.Net.Sockets.SocketException: An existing connection was forcibly closed by the remote host at System.Net.Sockets.NetworkStream.Read(Byte[] buffer, Int32 offset, Int32 size)

I worked on the problem for quite a while (many hours off and on over several days). Then I tried using a different provider for the email service. The same exact error occurred.

Frustrated, I would set it aside for a month or so and worked on it again on some weekends. No luck.

People realized that the web site actually accepted entries even if it had not been announced. Then, a couple months ago, to my great surprise, I discovered that about 10% of the time the email did work. WHAT?!! Is it a timing issue? I did lots of experiments without success.

Yesterday, I started doing web searches with various search parameters to try and find the solution. Somewhat buried on one web page I found a suggestion, put this in your C# program anyplace before you attempt to make your connection with the other server:

ServicePointManager.SecurityProtocol = SecurityProtocolType.Tls12;

Since the web page was several years old I first tried using Tls13, newer is better, right?

No luck.

So I tried the original suggestion, Tls12. This worked.

There was great joy in Boomershoot land!

I’m making the blog post about this so perhaps other people can find the answer more easily than I was able to.

The complete error (exception call stack) is below the fold.

Continue reading

Bullet and Shell Casing Forensics Are a Coin Flip

Quote of the Day

In discussing the Ames II Study, he similarly opined that inconclusive responses should be counted as errors. By not doing so, he contended, the researchers had artificially reduced their error rates and allowed test participants to boost their scores. By his calculation, when accounting for inconclusive answers, the overall error rate of the Ames II Study was 53% for bullet comparisons and 44% for cartridge case comparisons—essentially the same as “flipping a coin.” Regarding the other two phases of the Ames II Study, Dean Faigman found the rates of repeatability and reproducibility “shockingly low.”

Fader, C.J.
KOBINA EBO ABRUQUAH v. STATE OF MARYLAND
June 20, 2023

Good to know if you are ever falsely accused and they are using firearm forensics against you.

Via David Hardy.