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In experiments using a mouse model of colorectal cancer, researchers observed an extraordinary outcome after administering E. americana through a single intravenous injection. The treatment completely eliminated tumors in every case, resulting in a 100% complete response (CR) rate. This level of effectiveness was far greater than what is typically seen with established cancer therapies such as immune checkpoint inhibitors (anti-PD-L1 antibody) and the chemotherapy drug liposomal doxorubicin (chemotherapy agent).

Japan Advanced Institute of Science and Technology
April 10, 2026
Naturally Occurring Bacteria Completely Eradicate Tumors in Mice With a Single Dose

Looking at the “future directions” in the article, I found it odd there was no mention of moving toward use in treating human cancers. Perhaps other scientists will pick up on this and see if it works in humans.

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